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INTEGRAL LONGEVITY TECHNOLOGIES
Targeted physical activity for Healthy Longevity
We develop structured, clinically studied, targeted physical activity protocols — designed to enhance healthy longevity, wellbeing and performance.
Healthy Longevity means more healthy, active, capable years.
WHAT WE BUILD
Two protocols, one evidence-driven methodology
We develop targeted physical activity protocols, delivered on a digital platform. Feedback-based assessments adapt each programme to the individual and track progress over time.
PROTOCOL 1 · ADULTS 40+
Healthy Longevity
For adults aged 40 and over
A gentle, accessible, progressive protocol designed to help prevent age-related disease and extend healthspan — with no previous fitness background required.
PROTOCOL 2 · HIGH DEMAND
Upgraded Performance
For athletes and professionals under high, sustained stress
The same evidence-based methodology, adapted for performance, recovery and resilience — and tailored to specific goals.
THE PROBLEM
We live longer, but not healthier
The widening gap between lifespan and healthspan is filled with chronic, age-related disease.
The leading causes of preventable death and disability — cardiovascular disease, type 2 diabetes, dementia, cancer and frailty — are diseases of ageing. They share an important underlying mechanism: the chronic, low-grade systemic inflammation that builds quietly with age — inflammageing.
THE AIM
Target inflammageing
Inflammageing is increasingly recognised as a driving force behind many age-related diseases. By acting on its pathways, we aim to change the trajectory — fewer years lost to chronic disease, more years lived well.
Our targets:
Metabolic health
Low-grade systemic inflammation links ageing to metabolic syndrome, type 2 diabetes and chronic kidney disease. Acting on these pathways is a plausible lever for prevention.
Cardiovascular health
Inflammageing is implicated in age-related cardiovascular disease — a leading cause of lost healthy years and preventable death.
Functional resilience
Beyond disease, chronic low-grade inflammation may contribute to fatigue, pain and frailty — the everyday erosion of healthspan and quality of life.
OUR PROPRIETARY APPROACH
Targeted physical activity, designed to act on inflammageing pathways
Structured, mechanism-driven, reproducible protocols designed to act on the pathways of low-grade systemic inflammation and support functional health.
STEP 1 · ASSESS
Baseline
Questionnaires and, optionally, biomarkers establish a starting point.
STEP 2 · TAILOR
Personalise
The protocol is matched and adapted to the individual.
STEP 3 · RE-ASSESS
Track & adjust
Progress is tracked, and the plan adjusts over time.
Grounded in clinical research
Built on published and presented clinical research — not general wellness claims.
Mechanism-driven
Designed to target inflammageing pathways — the plausible roots of age-related diseases.
Feedback-adaptive
Questionnaire- and, optionally, biomarker-informed progression, delivered and tracked through the platform.
SCIENTIFIC EVIDENCE
Based on real clinical results
Our methodology is built on clinical research in inflammation-driven conditions — with further studies underway.
Inflammatory bowel disease
Published in the peer-reviewed Journal of Science and Medicine in Sport, December 2025.
A 4-week randomised, double-blind trial in 26 patients with mild-to-moderate inflammatory bowel disease. The targeted physical activity protocol was tested against general "placebo" exercise, not against rest. Both groups improved clinically. In the Crohn’s disease subgroup, remission reached 75% with the targeted protocol against 14% with general exercise. Faecal calprotectin, a standard marker of gut inflammation, remained stable in the targeted-activity group while increasing in controls.
Fibromyalgia
An early clinical study, presented at the 15th International Congress on Autoimmunity.
A non-randomised study in 30 adults with fibromyalgia: 15 followed the protocol, 15 continued their usual routine. 73% of the protocol group met the predefined pain-response threshold (significant improvements in symptoms such as pain and fatigue), against 13% of the others. Gut-barrier and microbiome markers shifted towards a healthier profile. Some of those findings survived statistical correction; others remain exploratory. Manuscripts in preparation.
Inflammageing
A randomised proof-of-concept pilot in adults over 40 — the next study.
The clinical studies above were in patients, which is not where most adults over 40 find themselves. What they notice instead - is a tiredness that rest no longer clears, a slower recovery, sleep that restores less, and a blood panel that comes back borderline. Nothing crossing a diagnostic threshold, yet the low-grade inflammation underlying age-related disease already measurable.The pilot now in preparation begins precisely there, following that group through 12 weeks of the Healthy Longevity protocol and assessing, before and after, validated measures of fatigue, sleep quality and physical function alongside inflammatory and gut-barrier markers. It turns evidence gathered in patients into evidence for the far larger group who are not yet ill — published in full, whatever it shows.
THE TEAM
Leadership grounded in science and experience
Yuri Ostrinski
FOUNDER & CEO
25+ years in medical, R&D and international healthcare projects management. Originator of the concept. Founder of several healthcare ventures. Responsible for management, strategy, partnerships and commercialisation.
Andrii Siderskyi
CO-FOUNDER · METHODOLOGY DIRECTOR
A world-leading expert in structured physical activity with 40+ years of experience. Creator of scalable, progression-based methods used by thousands of practitioners globally. Responsible for the methodology and design of the targeted protocols.
Prof. Yehuda Shoenfeld
SCIENTIFIC ADVISOR
A globally recognised immunologist and leading authority in autoimmunity, inflammation and immune-mediated disease, with an extensive record of clinical research and scientific leadership. Provides guidance on ILT’s inflammageing framework, biomarker strategy and research validation.
GET INVOLVED
Join us in building the next generation of research-led Healthy Longevity solutions
Whether you are an investor or a potential partner, we would welcome the conversation. Tell us a little about your interest and we will be in touch.
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